Before you write policy rules to either allow or block this traffic, you will want to determine if there are any traffic flows between them.
Using Illumio Xpress visualization tools you can query, for example, the following:
"Any traffic flows during the last week between my Development and Production environments, over any port except port 80, excluding any workloads that have a Role label named ‘Domain Controller’"
You would use the dropdown menus to select the above values. Once you are ready you would select Run.The results appear when the search criteria are met, and will default to the Table view. You can also select Map or Mesh from the drop-down list if you prefer.